Ozempic

Leslie Mann Reveals Why Judd Apatow Intentionally Gained Weight on Ozempic

Leslie Mann revealed that her husband Judd Apatow had a unique experience with Ozempic, sharing the director likes to “override" the feeling "Ozempic gives you to stop eating."

August 28, 2026

Chrissy Metz, Serena Williams and Oprah Winfrey Are Just Some of the Stars Using Weight Loss Drugs

Chrissy Metz told E! News she was reluctant to give GLP-1s a shot. Serena Williams, as well. But now that the weight loss medications have served up results, they and other celebs are telling all.

August 15, 2026

Exclusive

Ozempic Skincare Is a Thing—Here’s What Experts Want You to Know

Ozempic face is probably all over your feed—an expert explains why it happens and how to treat it. 

August 13, 2026

Alabama Barker Threatens to Go on "Highest Dose" of Ozempic as Clapback to "Disgusting" Body

Alabama Barker hit back at "disgusting" comments about her weight and appearance, telling trolls in a scathing video, "I'm gonna get on the highest dose of Ozempic."

August 1, 2026

Alabama Barker Threatens to Go on "Highest Dose" of Ozempic as Clapback to "Disgusting" Body Shamers

Alabama Barker hit back at "disgusting" comments about her weight and appearance, telling trolls in a scathing video, "I'm gonna get on the highest dose of Ozempic."

August 1, 2026

Rosie O’Donnell Details How 60-Lb. Weight Loss, Facelift Changed Her Life

Rosie O’Donnell—who revealed she got a facelift last May following a 60-lb. weight loss—detailed how her new look has changed her life: “It’s very strange to just buy a pair of jeans that fit.”

July 21, 2026

Trisha Paytas Details 26-Lb. Weight Loss in 6 Weeks on a GLP-1 Medication

Influencer Trisha Paytas shared that she lost 26 pounds over six weeks while using a GLP-1, saying she was grateful the medication helped her consume her favorite foods in moderation.

June 18, 2026

Kris Jenner Says Ozempic Side Effects Left Her "So Sick" She Couldn't Work

Kris Jenner reflected on her past use of Ozempic, detailing how she was quick to get off the medication amid adverse side effects.

May 7, 2026

Teddi Mellencamp Requested GLP-1s for Weight Loss Amid Cancer Battle

Real Housewives of Beverly Hills' Teddi Mellencamp shared that her doctor denied her request to be prescribed GLP-1s as she continues to battle stage 4 cancer.

April 24, 2026

Kendra Wilkinson Reveals Why She's Starting GLP-1 Medication

Kendra Wilkinson detailed her decision to start taking weight-loss injections nearly one year after first attempting to take the medication: "I just want to be balanced out."

March 24, 2026

Kendra Wilkinson Reveals Why She's Starting GLP-1 Medication

Kendra Wilkinson detailed her decision to start taking weight-loss injections nearly one year after first attempting to take the medication: "I just want to be balanced out."

March 24, 2026

The View’s Joy Behar Reveals How Much Weight She’s Lost Using a GLP-1

'The View' co-host Joy Behar revealed during the Feb. 18 episode of the popular daytime talk show that she's taken a GLP-1.

February 18, 2026

Exclusive

Serena Williams Tells Oprah Winfrey Why She Initially Thought Weight Loss Shots Were a “Shortcut”

Serena Williams discussed why she ultimately decided to use a GLP-1 medication to lose weight in E! News’ exclusive clip of her conversation with Oprah Winfrey on The Oprah Podcast.

January 13, 2026

Why Oprah Doesn't Even Recognize Herself Amid Health Journey

Oprah Winfrey candidly detailed her health and weight loss journey since starting GLP-1 medication, noting she can “hardly recognize” the woman she’s become.

December 31, 2025

Oprah Winfrey Details How Her Use of GLP-1 Medications Led to Sobriety

Oprah Winfrey explained that in addition to weight loss and renewed energy, her use of GLP-1 medications for weight loss also led her to stop drinking alcohol.

December 30, 2025

Oprah Reveals Use of GLP-1 Medications Led to Sobriety

Oprah Winfrey detailed that in addition to weight loss and renewed energy, her use of GLP-1 medications for weight loss also led her to stop drinking alcohol.

December 30, 2025

Serena Williams, Amy Schumer and Every Celeb Who Has Weighed in On Ozempic and Weight Loss Drugs

With Serena Williams, Amy Schumer, Andy Cohen, Meghan Trainor and more stars giving the various weight loss medicines a shot, it'd be easier to catalog which celebrities haven't weighed in on GLP-1s.

December 29, 2025

Amanda Bynes Reveals She Lost 28 Pounds With Ozempic

Amanda Bynes detailed her nearly 30-lb. weight loss while using injectable type 2 diabetes drug Ozempic, and how it has inspired her to continue with her health goals.

December 23, 2025

Amanda Bynes Shares She's Lost 28 Pounds After Using Ozempic

Amanda Bynes detailed her nearly 30-lb. weight loss while using injectable type 2 diabetes drug Ozempic, and how it has inspired her to continue with her health goals. 

December 23, 2025

Dr. Terry Dubrow Breaks Down Meaning of an “Ozempic Penis”

Dr. Terry Dubrow and Heather Dubrow explain one of the NSFW side effects related to men who take Ozempic or other semaglutide medications.

November 25, 2025

Dr. Terry Dubrow Breaks Down Meaning of an “Ozempic Penis” 

Dr. Terry Dubrow and Heather Dubrow explain one of the NSFW side effects related to men who take Ozempic or other semaglutide medications. 

November 25, 2025

Amy Schumer Deletes Her Pre-Weight Loss Social Media Photos

Amy Schumer deleted all her Instagram photos that debuted her weight loss transformation, but she kicked off her grid with a new look at her figure.

November 12, 2025